High-energy brain dynamics during anesthesia-induced unconsciousness

A transition in brain state during propofol-induced unconsciousness.

Rhythmic oscillations shape cortical dynamics during active behavior, sleep, and general anesthesia. Cross-frequency phase-amplitude coupling is a prominent feature of cortical oscillations, but its role in organizing conscious and unconscious brain states is poorly understood. Using high-density EEG and intracranial electrocorticography during gradual induction of propofol general anesthesia i...

The changes of oligodendrocytes induced by anesthesia during brain development

Post-reperfusion Coagulopathy Hyperventilation-induced Unconsciousness during Labour

Sir,—In commenting on our paper [1], Kardos, Rudas and Simon described their own use of the analysis of short-term heart rate variability to assess the effect of varying posture on cardiac autonomic control. Essentially they have confirmed that head-up tilt causes sympathetic activation (as evidenced by an increase in the low frequency variability) in comparison with supine and head-down positi...

Thalamocortical synchronization during induction and emergence from propofol-induced unconsciousness.

General anesthesia (GA) is a reversible drug-induced state of altered arousal required for more than 60,000 surgical procedures each day in the United States alone. Sedation and unconsciousness under GA are associated with stereotyped electrophysiological oscillations that are thought to reflect profound disruptions of activity in neuronal circuits that mediate awareness and cognition. Computat...

Anesthesia and neuroimaging: investigating the neural correlates of unconsciousness.

In the past 15 years, rapid technological development in the field of neuroimaging has led to a resurgence of interest in the study of consciousness. However, the neural bases of consciousness and the boundaries of unconscious processing remain poorly understood. Anesthesia combined with functional neuroimaging presents a unique approach for studying neural responses as a function of consciousn...